BMC Proceedings

Table 1 Results for selected candidate genes

From: Case-control studies with affected sibships

			GAW data set
	Allele frequency		F_ST		p-value
Gene/marker	Case	Control	ANOVA	ANOVA	no linkage	χ²-test	p-value^a
PTPN22/rs2476601	0.17	0.08	0.25	<0.0001	<0.0001	<0.0001	<0.0001
CTLA4/CT60	0.39	0.45	0.23	0.0051	0.0054	0.0019	0.0010
HAVCR1/5509_5511delCAA	0.20	0.23	0.22	0.0223	0.0241	0.0117	0.99
SUM04/rs237025	0.51	0.46	0.25	0.0022	0.0026	0.0008	0.99
SUM04/rs577001	0.39	0.35	0.23	0.0280	0.0323	0.0166	-

^aOne-sided p-values for the allelic χ² test given by Plenge et al. If the association was not concordant to previous studies, these p-values were set to 0.99 [6].

Back to article page

ISSN: 1753-6561

Contact us

Submission enquiries: supplements@biomedcentral.com
General enquiries: ORSupport@springernature.com