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Table 4 Previously identified non-chromosome 6 loci or regions that contribute to the risk of RA

From: A search for non-chromosome 6 susceptibility loci contributing to rheumatoid arthritis

Locus

Location

Type of variation

Reference

SLC22A4

5q31

Intronic SNP

Tokuhiro et al. [10]

RUNX1

21q22.3

Intronic SNP

Tokuhiro et al. [10]

PADI4

1p36.13

Production of RA-specific autoantibodies

Suzuki et al. [11]

PTPN22

1p13

Non-synonymous coding SNP

Begovich et al. [12]

MHC2TA

16p13

SNP in the type III of the MHC class II transactivator

Swanberg et al. [13]

STAT4

2q32.2-3

Intronic SNP

Remmers et al. [14]

TRAF1-C5

9q33-34

A 100-kb region

Plenge et al. [7]