Figure 1

Classification tree generated by GUIDE. For each SNP, an additive genetic model with respect to the minor allele was used. At each intermediate node, a case went to the left child node if and only if the condition was satisfied. The classification tree generated by GUIDE had 17 terminal nodes (yellow or green). Node numbers were labeled at the terminal nodes. Nodes in yellow were controls (coded as 1) and nodes in green were cases (coded as 2). There were 228 cases in the sample. Predicted class and number of errors divided by number of cases are given beneath each terminal node. The current tree in Figure 1 pruned by ten-fold cross-validation has the smallest misclassification cost.