Assessment of gene-covariate interactions by incorporating covariates into association mapping

BMC Proceedings

Table 4 Association analysis of individual SNPs with a p-value < 1.0 × 10^-30

SNP	Base pair	Minor^a allele	MAF in cases	MAF in controls	Chi-square statistic	p-Value	OR
rs6910071	32,390,830	G	0.5212	0.1952	435.6	1.00 × 10^-96	4.488
rs9268368	32,441,930	G	0.6163	0.397	170.7	5.33 × 10^-39	2.44
rs3129941	32,445,660	A	0.09517	0.2496	135.8	2.20 × 10^-31	0.3163
rs2395157	32,456,120	G	0.5339	0.2767	247.4	9.41 × 10^-56	2.994
rs3117098	32,466,490	G	0.1374	0.306	137	1.23 × 10^-31	0.3612
rs2076530	32,471,790	A	0.2826	0.5553	265.5	1.08 × 10^-59	0.3154
rs6932542	32,488,240	A	0.2144	0.4719	249.5	3.33 × 10^-56	0.3054
rs9268615	32,510,870	A	0.5928	0.3774	165.7	6.56 × 10^-38	2.401
rs2395173	32,512,840	A	0.1433	0.3466	185.4	3.23 × 10^-42	0.3152
rs3129882	32,517,510	G	0.1955	0.4261	209.9	1.43 × 10^-47	0.3273
rs7192	32,519,620	A	0.1643	0.3916	215.2	1.00 × 10^-48	0.3055
rs6903608	32,536,260	G	0.1007	0.3116	220	8.99 × 10^-50	0.2475
rs2516049	32,678,380	G	0.583	0.3059	279.9	8.02 × 10^-63	3.172
rs660895 ^b	32,685,360	G	0.5382	0.1927	485.4	1.42 × 10^-107	4.884
rs5000634	32,771,540	G	0.61	0.3827	183	1.10 × 10^-41	2.523
rs6457617	32,771,830	G	0.1861	0.491	343.6	1.03 × 10^-76	0.2371
rs9275312	32,773,710	G	0.2953	0.1213	177.2	1.97 × 10^-40	3.035
rs9275388	32,777,060	G	0.4942	0.2412	249.3	3.64 × 10^-56	3.074
rs2858305	32,778,440	C	0.1551	0.3749	206.7	7.19 × 10^-47	0.3061
rs7745656	32,788,950	A	0.1084	0.289	166.2	5.02 × 10^-38	0.2992

ISSN: 1753-6561