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Table 1 LRT and p-values for the association between SNPs and longitudinal SBP for the main genetic effect (LRT1), genotype-by-age interaction (LRT2), and combined main effects and genotype-by-age interaction (LRT3)

From: Longitudinal age-dependent effect on systolic blood pressure

     

Genetic effect

Genotype-by-age effect

Genetic + genotype-by-age effects

SNPa

Chrb

Position

Alleles

MAF

LRT1

-log(p)

LRT2

-log(p)

LRT3

-log(p)

rs17631940

17

30842243

A/G

0.49

23.99

6.01

1.02

0.50

25.00

5.43

rs1476112

18

170690

T/G

0.08

14.40

3.83

13.43

3.61

27.83

6.04

rs8102150

19

922139

G/C

0.03

7.05

2.10

23.09

5.81

30.14

6.55

  1. aOnly SNPs with a Bonferroni-corrected p-value ≤ 10-7 (-log(p) ≥ 6) in at least one of the tests are shown.
  2. bChr, chromosome; MAF, minor allele frequency