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Table 1 Major-gene SNP tests with the first replication of the simulated GAW16 data using linear mixed-effects models with Kronecker and hierarchical structures

From: Application of three-level linear mixed-effects model incorporating gene-age interactions for association analysis of longitudinal family data

  

UN+CSa

UN⊗CSb

Major gene

SNP

AIC

-Log P1c

-Log P2d

AIC

-Log P1

-Log P2

Ï„ 1

rs6743961

34355.67

0.03

0.12

34356.60

0.00

0.01

Ï„ 2

rs17714718

34365.19

5.42

6.15

34365.66

4.88

5.63

Ï„ 3

rs1894638

34352.03

0.23

0.04

34352.82

0.24

0.06

Ï„ 4

rs1919811

34354.41

0.02

0.11

34355.51

0.47

0.07

Ï„ 5

rs213952

34372.39

>16

0.21

34373.04

>16

0.29

  1. aMixed-effects model with three-level hierarchical structure
  2. bMixed-effects model with Kronecker structure
  3. cP1, p-values of genotype tests
  4. dP2, p-values of additive model tests
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BMC Proceedings

ISSN: 1753-6561

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