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Table 1 measurement ranges current methods versus Cedex Bio

From: Utilizing Roche Cedex Bio analyzer for in process monitoring in biotech production

Parameter

Current methods

Cedex Bio

Cedex Bio

  

w/o dilution

automated dilution

glucose [mg/L]

200 – 15.000 1)

20 – 7.500

20 – 75.000

lactate [mg/L]

200 – 5.000 1)

18 – 1.400

18 – 14.000

ammonia [mg/L]

3,6 – 450 1)

0.48 – 12

0.48 – 480

glutamine [mg/L]

30 – 877 1)

60 – 1.500

60 – 7.500

glutamate [mg/L]

30 – 882 1)

15 – 1.500

15 – 7.500

sodium [mg/L]

920 – 5.006 2)

460 – 5.750

460 – 5.750

potassium [mg/L]

39,1 – 978 2)

39 – 1.170

39 – 1.170

LDH [U/L]

20 – 150 3)

20 – 1.000

20 – 10.000

IgG [mg/L]

35 – 1.500 4)

10 – 1.600

10 – 16.000

  1. 1) Membrane analyzer, 2) Ion selective electrode 3) 96-well-plate assay, 4) HPLC method