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Figure 1 | BMC Proceedings

Figure 1

From: Process development of ATROSAB, an anti TNFR1 Monoclonal Antibody: in three steps from research to GMP

Figure 1

The left diagram shows the cell density of two GMP runs in the 300L bioreactor. The right diagram focuses on the achieved product concentrations during the different process development steps. The batch experiment was performed in 1L bioreactors, the feed screening was done in 250 mL shake flasks. The feed optimization was performed in 10L bioreactors and the GMP runs were done in a 300L stirred tank bioreactor in a GMP facility.

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BMC Proceedings

ISSN: 1753-6561

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