Figure 1

Fed-batch experiments for production of IgG B. The fast-track cell line (left hand graph) was cultivated at 10 L scale after two steps of process development and scale up using chemically defined basal and feed medium. The optimized cell line (right hand graph) was cultivated at 1 L scale after basal media and feed media screening. A chemically defined medium was used in combination with the proprietary feed solution CeloFeed.