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Figure 2 | BMC Proceedings

Figure 2

From: Analysis of glycolytic flux as a rapid screen to identify low lactate producing CHO cell lines with desirable monoclonal antibody yield and glycan profile

Figure 2

The effect of different carbon sources on ECAR from lactic acid production and on metabolic shift in CHO_mAb. Change of baseline ECAR of CHO_mAb cells after Carbon/nitrogen source injection versus time (A). Glucose and mannose preference for aerobic glycolysis(B) Comparison of maximum ECAR in XF96 with lactic acid in shake flasks showed an excellent correlation, R2=0.91 (C)

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