Figure 1From: Determination of intracellular antibody production, cell density, and viability of recombinant CHO-DG44 cells using the MACSQuant® Analyzer(A) The time course of an unstable MTX amplification is presented. A decrease in the fraction of IgG-producing cells (FP) is caused by resistance to increasing MTX concentrations (cMTX). (B) Dot plots for the samples at 307 h (160 nM MTX) and 687 h (640 nM) are shown. IgG-producing cells appear in the upper right gates.Back to article page