Table 1 Viable cell density (VCD) and cell viabilities of CHO cells cultured in a fed-batch bioreactor process
Process time (d) | VCD mean (cells/mL) | STDV | CV (%) | Viability mean (%) | STDV | CV (%) | |
|---|---|---|---|---|---|---|---|
Cedex | 0.8 | 7.33E+05 | 1.35E+04 | 1.8 | 96.39 | 0.92 | 1.0 |
3.8 | 4.18E+06 | 5.94E+04 | 1.4 | 97.01 | 0.33 | 0.3 | |
MACSQuant Analyzer | 0.8 | 6.47E+05 | 9.42E+03 | 1.5 | 95.30 | 0.03 | 0.0 |
3.8 | 4.41E+06 | 2.87E+04 | 0.7 | 96.06 | 0.06 | 0.1 | |
Vi-Cell | 0.8 | 7.11E+05 | 1.06E+05 | 14.9 | 96.31 | 0.73 | 0.8 |
3.8 | 5.03E+06 | 9.92E+04 | 2.0 | 96.98 | 0.06 | 0.1 |