Identification of multiple rare variants associated with a disease

BMC Proceedings

Table 1 Minor allele frequencies of SNPs within two randomly selected genes

Gene	Chromosome	SNP	Function	Minor allele	Minor allele frequency
					All*	Europeans	Asians	Africans
CFH	1	C1S8678	Nonsynonymous	A	0.341	0.032	0.579	0.982
		C1S8682	Synonymous	C	0.001	0	0	0.005
		C1S8684	Synonymous	A	0.311	0.923	0.106	0.964
		C1S8686	Nonsynonymous	C	0.325	0.942	0.134	0.959
SMAD7	18	C18S2642	Synonymous	C	0.006	0	0.022	0
		C18S2643	Synonymous	A	0.009	0	0.034	0
		C18S2648	Synonymous	T	0.006	0	0.028	0

ISSN: 1753-6561