Figure 2

Increasing the sample size by enriching or widening the tails and effect on power. The power to detect each of the nine genes including causal SNPs for Q1 using linear regression and the beta test with increased sample size. Orange dots refer to the analyses enriched by adding further individuals with extreme trait values: (A) One additional replicate was added to gain 40% of the original sample size; (B) two additional data sets were added to gain 60% of the original sample size. Green dots represent the analyses based on the widened tails: (A) top 20% versus bottom 20%; (B) top 30% versus bottom 30%. Power was calculated as the percentage of nominally significant p-values using the first 100 replicates.