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Table 3 Relative power (in relation to the maximum-likelihood estimate) of hierarchical modeling method at FDR = 0.05

From: Enhancing the discovery of rare disease variants through hierarchical modeling

Variation

Trait Q1

Trait Q2

UNINF

0.94

1.14

Z only

0.98

1.17

A only

1.04

1.17

FULL

1.05

1.19

  1. FDR, false discovery range.