Enhancing the discovery of rare disease variants through hierarchical modeling

BMC Proceedings

Table 4 Bayes factors for each causal variable under the Q1 trait model

Causal variable^a	UNINF	Z only	A only	FULL
ARNT, nonsynonymous	1.14	1.95	1.85	3.99
C4S1884	36.33	43.31	36.12	47.65
HIF1A, nonsynonymous	0.58	1.14	0.57	1.22
C13S522	527.13	600.4	764.92	773.35
C1S6533	109.38	149.45	119.39	162.42
C4S1878	57.23	92.15	69.16	107.15
C14S1734	1.47	2.42	1.47	2.58
C13S431	299.20	327.49	572.87	551.06
FLT1, nonsynonymous	17.25	27.80	81	103.17
C13S523	998.33	999.07	999.87	999.7

^a Defined as either a bin of SNPs (shown with convention gene name and mutation class) or a single SNP. Only variables with MAF ≥ 0.01 were included for analyses.

ISSN: 1753-6561