Identification of genes and variants associated with quantitative traits using Bayesian factor screening

BMC Proceedings

Table 4 Genes with high marginal posterior probabilities

Appearances in the top 10 genes among 10 replicates	m = 3	m = 6
10	FLT1	FLT1
6	−	KDR
5	KDR	−
2	Two genes not associated with Q1	Four genes not associated with Q1
1	ARNT, HIF1A, 79 genes not associated with Q1	HIF1A, VEGFA, 74 genes not associated with Q1

The genes that have posterior probabilities in the top 10, including both Q1-associated genes and false positives, are listed. The symbols of Q1-associated genes are given and those not associated with Q1 are omitted. The first column shows the frequency of a variant in the top 10 among 10 replicates. The second and third columns show the results at m = 3 and m = 6, respectively, where m is the fixed number of factors entertained in a model of the model space.

ISSN: 1753-6561