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Table 3 Comparison of number of significant genes using trait Q1

From: Comparison of SNP-based and gene-based association studies in detecting rare variants using unrelated individuals

α

SNP

GL

G2

 

True

False

Total

True

False

Total

True

False

Total

1 × 10−5

1

2

3

2

1

3

1

3

4

1 × 10−4

1

4

5

2

6

8

1

4

5

1 × 10−3

2

19

21

2

23

25

1

12

13

0.01

2

73

75

3

101

104

1

75

76

0.10

4

389

393

5

397

402

4

303

307

0.25

5

718

723

6

695

701

7

626

633

0.50

6

1,266

1272

7

1,246

1,253

8

969

977

  1. SNP, GL, and G2 are the SNP-based, gene-based linear, and gene-based two-step methods, respectively. The “True” columns are number of true associated genes; the “False” columns are number of false-positive genes; the “Total” columns are the total number of positive genes detected.