Large-scale risk prediction applied to Genetic Analysis Workshop 17 mini-exome sequence data

BMC Proceedings

Table 3 Cross-validation error and AUC value for the three methods

Item	Model	Statistic	Empirical Bayes method	Weighted empirical Bayes method	Joint covariance model
Cross-validation error	Gene + environment	Mean	0.26	0.24	0.24
		SE	0.0020	0.0011	0.0012
AUC value	Gene + environment	Mean	0.76	0.80	0.78
		SE	0.0102	0.0015	0.0148
AUC value	Gene	Mean	0.60	0.64	0.62
		SE	0.0191	0.0183	0.0191

AUC is the area under the ROC curve when minimizing the cross-validation error. SE, standard error of the cross-validation error and the AUC value.

ISSN: 1753-6561