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Table 1 MCMC analysis: chromosome-wide p-values

From: Methods for detecting associations between phenotype and aggregations of rare variants

 

Q1

Q2

Q4

Chromosome

Unadjusted

Adjusted

Unadjusted

Adjusted

Unadjusted

Adjusted

1

0.020

0.148

0.688

0.594

0.061

0.213

2

0.001

0.285

0.217

0.348

0.542

0.403

3

0.026

0.240

0.117

0.811

0.810

0.593

4

0.002

0.414

0.191

0.183

0.202

0.641

5

0.008

0.841

0.050

0.658

0.544

0.038

6

0.002

0.014

0.187

0.050

0.002

0.022

7

0.001

0.017

0.003

0.459

0.507

0.333

8

0.044

0.164

0.068

0.939

0.351

0.875

9

0.022

0.232

0.174

0.869

0.001

0.124

10

0.002

0.844

0.183

0.390

0.586

0.532

11

0.002

0.223

0.601

0.874

0.266

0.357

12

0.010

0.267

0.310

0.692

0.551

0.235

13

0.001

0.001

0.097

0.047

0.266

0.707

14

0.001

0.006

0.64

0.832

0.551

0.808

15

0.140

0.563

0.923

0.663

0.006

0.571

16

0.016

0.229

0.198

0.190

0.269

0.245

17

0.008

0.464

0.499

0.694

0.355

0.680

18

0.004

0.037

0.945

0.958

0.033

0.046

19

0.001

0.034

0.519

0.368

0.514

0.570

20

0.904

0.003

0.053

0.586

0.034

0.224

21

0.597

0.611

0.076

0.552

0.015

0.064

22

0.002

0.633

0.170

0.831

0.008

0.628

  1. Chromosome-level p-values for each quantitative trait using the Madsen-Browning statistic, replicate 1. Results are shown before (unadjusted) and after (corrected) PC correction for population stratification. Results for chromosomes containing SNPs that are directly associated with the corresponding trait (per the GAW17 answers) are shown in boldface.
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BMC Proceedings

ISSN: 1753-6561

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