Skip to main content

Table 2 GA analysis: chromosome-wide p-values

From: Methods for detecting associations between phenotype and aggregations of rare variants

 

Q1

Q2

Q4

Chromosome

Unadjusted

Adjusted

Unadjusted

Adjusted

Unadjusted

Adjusted

1

0.018

0.506

0.385

0.632

0.149

0.015

2

0.001

0.001

0.311

0.401

0.137

0.769

3

0.017

0.912

0.235

0.958

0.364

0.371

4

0.006

0.021

0.054

0.726

0.136

0.089

5

0.002

0.128

0.041

0.947

0.082

0.067

6

0.001

0.003

0.169

0.209

0.019

0.013

7

0.002

0.070

0.067

0.665

0.017

0.422

8

0.258

0.140

0.646

0.473

0.078

0.220

9

0.017

0.124

0.124

0.103

0.065

0.061

10

0.196

0.003

0.174

0.434

0.042

0.362

11

0.006

0.032

0.609

0.869

0.190

0.702

12

0.017

0.073

0.393

0.730

0.167

0.178

13

0.001

0.002

0.482

0.568

0.427

0.060

14

0.002

0.001

0.958

0.404

0.295

0.160

15

0.541

0.266

0.422

0.269

0.254

0.579

16

0.156

0.401

0.280

0.364

0.235

0.643

17

0.588

0.403

0.619

0.966

0.509

0.598

18

0.012

0.056

0.417

0.840

0.464

0.670

19

0.067

0.014

0.262

0.554

0.041

0.479

20

0.152

0.006

0.048

0.204

0.054

0.136

21

0.663

0.073

0.006

0.250

0.088

0.065

22

0.004

0.062

0.127

0.108

0.072

0.095

  1. Chromosome-level p-values for each quantitative trait using the Madsen-Browning statistic, replicate 1. Results are shown before (unadjusted) and after (corrected) PC correction for population stratification. Results for chromosomes containing SNPs that are directly associated with the corresponding trait (per the GAW17 answers) are shown in boldface.