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Table 3 MCMC analysis: chi-square test for detection of causal SNPs

From: Methods for detecting associations between phenotype and aggregations of rare variants

Q1

Q2

Chromosome

p-value

Chromosome

p-value

1

1.1 × 10−2

2

0

4

1.5 × 10−8

3

3.5 × 10−3

5

1.7 × 10−1

6

0

6

0

7

4.2 × 10−2

13

0

8

7.7 × 10−7

14

2.0 × 10−1

9

4.6 × 10−1

19

8.5 × 10−1

10

1.2 × 10−2

  

12

2.4 × 10−1

  

17

4.2 × 10−1

  1. We report p-values resulting from a chi-square test for nonrandom association, across the 200 replicates of the GAW17 data, between those SNPs that were included in the best aggregation of SNPs found by our MCMC analysis and those that were actually causal (assessed by referencing the GAW17 answers). Analysis was performed after correction for population stratification using 10 PCs.