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Table 1 Distributions of the number of causal SNPs significantly correlated (r Ï„ j > 0.1) with each SNP

From: Power of association tests in the presence of multiple causal variants

Data set

Number of correlated (r Ï„j > 0.1) causal SNPs

 

0

1

2

3

4

5

6

7

>7

GAW17

13,288

5,153

2,402

870

424

278

136

85

121

Simulated data

14,322

5,229

2,092

729

245

104

29

7

0

  1. For each SNP in the GAW17 data and in the simulated data, we count how many of the 39 causal SNPs in the GAW17 data have correlation coefficients r Ï„j > 0.1 with it. We find that 9,469 SNPs in the GAW17 data and 8,435 SNPs in the simulated data are correlated (r Ï„j > 0.1) with at least one causal SNP. Note that in the simulated data set, all SNPs are simulated to be in linkage equilibrium with each other and with the 39 causal SNPs, so all observed correlations are due to chance alone.