A method to detect single-nucleotide polymorphisms accounting for a linkage signal using covariate-based affected relative pair linkage analysis

Table 1 Causal SNPs within the top 5% of SNPs

Chromosome	SNP	LodDiff	Gene	Minor allele frequency	Effect	p-value
4	C4S4935	9.09	VEGFC	0.000717	1.35726	0.0000813
6	C6S2981	4.01	VEGFA	0.002152	1.20645	0.0000201
10	C10S3109	2.20	SIRT1	0.000717	0.51421	0.0000112
4	C4S1878	1.45	KDR	0.164993	0.13573	0.0022138
8	C8S442	1.12	LPL	0.015782	0.49459	NA

The information on five causal SNPs within the top 5% of SNPs from the ordered LodDiff values are shown. The p-values in the last column are from the family-based association analysis.

ISSN: 1753-6561