Table 1 p-Values and ORs for different effects
From: A pathway-based association analysis model using common and rare variants
| Â | Â | Â | Combined effects | |||||
|---|---|---|---|---|---|---|---|---|
| Â | Rare variant effects, unadjusted | Common variant effects, unadjusted | Unadjusted | Adjusted by clinical factorsa | ||||
Pathway | p-value | OR | p-value | OR | p-value | OR | p-value | OR |
STEMCELL_EMBRYONIC_UP | 0.001 | 1.09 | 2.28 × 10−20 | 1.34 | 1.65 × 10−19 | 1.06 | 4.83 × 10−22 | 1.1 |
LEE_TCELLS2_UP | 0.012 | 1.06 | 7.44 × 10−19 | 1.33 | 2.74 × 10−16 | 1.05 | 2.09 × 10−21 | 1.09 |
DAC_PANC_UP | 0.39 | 1.06 | 3.44 × 10−16 | 1.3 | 1.72 × 10−15 | 1.07 | 1.79 × 10−17 | 1.12 |
AGED_RHESUS_UP | 0.003 | 1.24 | 1.02 × 10−12 | 1.33 | 2.51 × 10−13 | 1.09 | 1.79 × 10−15 | 1.15 |
ICHIBA_GVHD | 0.287 | 1.09 | 3.56 × 10−13 | 1.41 | 1.18 × 10−12 | 1.12 | 8.53 × 10−14 | 1.16 |
BRCA_ER_NEG | 0.009 | 1.07 | 5.40 × 10−11 | 1.22 | 4.48 × 10−12 | 1.08 | 9.94 × 10−17 | 1.13 |
HSC_HSC_ADULT | 0.018 | 1.11 | 4.26 × 10−12 | 1.29 | 5.84 × 10−12 | 1.09 | 1.49 × 10−12 | 1.14 |