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Table 1 Type I error rate and empirical power of tests for 125 SNPs in the VEGF pathway

From: Does pathway analysis make it easier for common variants to tag rare ones?

Method

Type I error rate

Empirical power

Global test

0.044

0.41

GRASS

0.047

0.43

Empirical Bayes

0.055

0.05

Weighted global test

0.041

0.65