Table 1 Summary of environmental effects for traits systolic blood pressure(top), diastolic blood pressure(middle) and Q1 (bottom) in simulation replicate SIMPHEN.1

LM

LMM

119.360

(0)

119.739

(0)

0.135

(2 × 10⁻¹¹)

0.168

(1 × 10⁻¹¹)

13.088

(7 × 10⁻⁹¹)

6.981

(0)

0.284

(6 × 10⁻¹)

0.556

(4 × 10⁻¹)

−19.547

(1 × 10⁻⁴⁹)

−20.985

(0)

0.387

(4 × 10⁻⁴³)

0.418

(0)

DBP

$\mu$

${\beta }_{Age}$

${\beta }_{BPMed}$

${\beta }_{Smoke}$

${\beta }_{Sex}$

${\beta }_{Age\times Sex}$

LM

LMM

75.781

(0)

75.382

(0)

−0.052

(7 × 10⁻⁴)

−0.032

(8 × 10⁻²)

1.893

(7 × 10⁻⁵)

−0.751

(1 × 10⁻¹)

−0.109

(8 × 10⁻¹)

−0.087

(9 × 10⁻¹)

−8.201

(2 × 10⁻¹⁶)

−8.305

(7 × 10⁻¹²)

0.124

(5 × 10⁻⁹)

0.131

(3 × 10⁻⁷)

Q1

$\mu$

${\beta }_{Age}$

${\beta }_{BPMed}$

${\beta }_{Smoke}$

${\beta }_{Sex}$

${\beta }_{Age\times Sex}$

LM

LMM

38.642

(0)

39.115

(0)

−0.087

(2 × 10⁻³)

−0.079

(1 × 10⁻³)

−2.508

(3 × 10⁻²)

−2.211

(3 × 10⁻²)

0.270

(7 × 10⁻¹)

0.239

(7 × 10⁻¹)

8.904

(4 × 10⁻⁸)

8.809

(1 × 10⁻⁹)

0.005

(9 × 10⁻¹)

0.000

(9 × 10⁻¹)