Table 1 Regression analysis summarizing association of model parameters and model performance across 315 different situations

Gene expression noise (k)

−3.5 × 10⁻² (1.2 × 10⁻²)**

−6.4 × 10⁻² (2.0 × 10⁻²)**

−3.3 × 10⁻² (1.7 × 10⁻²)

Number of collapsed phenotypes (m)

−4 × 10⁻⁵ (1.1 × 10⁻⁵)***

−5.49 × 10⁻⁶ (1.7 × 10⁻⁵)

−4.4 × 10⁻⁵ (1.5 × 10⁻⁵)**

Number of causal genes

−7.5 × 10⁻⁴ (1.7 × 10⁻⁴)***

−8.2 × 10⁻⁴ (2.7 × 10⁻⁴)**

−1.6 × 10⁻⁴ (2.3 × 10⁻⁴)

Number of random genes

−1.7 × 10⁻³ (3.6 × 10⁻⁵)***

−9.8 × 10⁻⁴ (5.6 × 10⁻⁵)***

−1.0 × 10⁻³ (4.8 × 10⁻⁵)***

Model r²

88.4 %

50.7 %

62.5 %