Table 3 Power comparisons of FBAT-v with different weighting schemes for SBP/DBP
From: Testing rare variants for hypertension using family-based tests with different weighting schemes
Gene | Power of Tests | ||||
|---|---|---|---|---|---|
FBAT-v-e | FBAT-v-e-grv | FBAT-v-e-lor | FBAT-v-e-ow | FBAT-v-e-fp | |
Significance level = 0.05 |  | ||||
MAP4 | 0.63/0.505 | 0.65/0.53 | 0.51/0.47 | 0.68/0.56 | 0.65/0.52 |
TNN | 0.015/0.03 | 0.01/0.03 | 0.02/0.01 | 0/0.02 | 0.06/0.04 |
NRF1 | 0/0.025 | 0/0.01 | 0.01/0 | 0.03/0.02 | 0.05/0.03 |
LEPR | 0.035/0.04 | 0.04/0.01 | 0.03/0.01 | 0.05/0.03 | 0.04/0.035 |
FLT3 | 0/0.025 | 0.02/0.04 | 0/0.01 | 0.04/0.05 | 0/0.03 |
Significance level = 0.1 |  | ||||
MAP4 | 0.82/0.715 | 0.86/0.74 | 0.71/0.62 | 0.85/0.765 | 0.83/0.74 |
TNN | 0.075/0.085 | 0.08/0.1 | 0.09/0.115 | 0.1/0.16 | 0.22/0.19 |
NRF1 | 0.035/0.1 | 0.03/0.125 | 0.02/0.09 | 0.06/0.185 | 0.08/0.145 |
LEPR | 0.07/0.105 | 0.05/0.09 | 0.08/0.135 | 0.11/0.2 | 0.1/0.12 |
FLT3 | 0.035/0.1 | 0.05/0.13 | 0.04/0.11 | 0.055/0.15 | 0.04/0.13 |
Significance level = 0.2 |  | ||||
MAP4 | 0.90/0.865 | 0.92/0.87 | 0.85/0.77 | 0.95/0.89 | 0.94/0.85 |
TNN | 0.17/0.2 | 0.15/0.22 | 0.18/0.21 | 0.15/0.255 | 0.29/0.33 |
NRF1 | 0.155/0.195 | 0.18/0.21 | 0.14/0.18 | 0.2/0.24 | 0.17/0.22 |
LEPR | 0.07/0.165 | 0.08/0.175 | 0.09/0.19 | 0.14/0.22 | 0.11/0.17 |
FLT3 | 0.135/0.195 | 0.15/0.18 | 0.17/0.22 | 0.195/0.17 | 0.15/0.215 |