A multistep approach to single nucleotide polymorphism–set analysis: an evaluation of power and type I error of gene-based tests of association after pathway-based association tests

Table 1 Settings for creation of synthetic pathways

Genes were randomly sampled without replacement and placed into sets of genes, or pathways, of varying sizes. The percent of genes in the pathway containing at least 1 causal variant also varied across sets

ISSN: 1753-6561