Table 1 (abstract P-047). Strategies for static and dynamic fed-batch development
Fed-batch protocol | Fundamentals for daily feed additions |
|---|---|
Static | Constant, daily feed additions |
Dynamic – Concentration | Key substrate kept at target concentration |
Dynamic – Predictive | Prediction of integrated viable cell count and cell-specific consumption rates of key substrate |
Dynamic – Retrospective | Based on mean daily gains of viable cell concentration and mean cell-specific consumption rates of previous experiments |