Abstracts from the Student Medical Summit 2023

Table 1 (abstract A7). Binding affinity of C.Gigantea phytochemicals and Imatinib with SERPINE1

	Binding affinity with SERPINE1
	K_i(μM)^a	IC₅₀(μM)^b
Nicotiflorin	329.6 ± 3.6	659.2 ± 6.1
Mefruside	557.8 ± 2.6	1115.7 ± 8.7
Quercetin	146.1 ± 5.6	292.8 ± 11.3
Zingerone	477.7 ± 4.2	955.1 ± 6.4
Imatinib^c	858.8 ± 6.5	1717.7 ± 9.1

^aK_i is the binding affinity of C.Gigantea phytochemicals and imatinib with SERPINE1
^bIC₅₀ is the efficacy of the C.Gigantea phytochemicals and imatinib to inhibit SERPINE1
^cImatinib was used as a reference compound

ISSN: 1753-6561