From: A genome-wide ordered-subset linkage analysis for rheumatoid arthritis
 |  |  |  | Penetrancea |  |  |  |  |  |  |  | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Covariate | Chr. no. | No. ordered subset families | Disease allele frequency | f1 | f2 | f3 | Position (cM) of peak MOD score | Peak MOD score | HLOD (α) | NPL score | p-Value | Position of peak MOD for ASM | Nonparametric LOD |
Age of Onset | 4 | 472 | 0.19 | 0.01 | 0.015 | 0.1 | 46.74 | 6.1 | 6.14 (0.89) | 4.56 | 0.000002 | 96.27 | 6.03 |
 | 9 | 27 | 0.03 | 0 | 0.08 | 1 | 6.6 | 3.41 | 3.41 (0.99) | 2.85 | 0.002 | 4.93 | 2.91 |
Anti-CCP level | 2 | 219 | 0.18 | 0.01 | 0.015 | 0.1 | 151.68 | 4.09 | 4.08 (0.96) | 3.72 | 0.0001 | 156.45 | 4.03 |
 | 18 | 40 | 0.13 | 0 | 0.99 | 1 | 24.69 | 5.44 | 5.44 (0.99) | 3.81 | 0.00008 | 24.69 | 5.03 |
 | 19 | 10 | 0.07 | 0 | 0 | 0.04 | 52 | 3.32 | 3.32 (0.99) | 3.28 | 0.0003 | 51.13 | 2.29 |