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Table 2 Two-locus models for the pooled data: NARAC, Canada-Illumina, France, and the first screen of UK

From: One- and two-locus models for mapping rheumatoid arthritis-susceptibility genes on chromosome 6

Type of analysis and ARPs No. ARP Estimate (95% CI) for
   τ1 (cM) τ2 (cM) λ 1 λ 2
Unconstrained model      
   Full siblings 1292    1.6 (1.4–1.8) 1.2 (1.0–1.3)
   Half siblings 45    1.8 (0.4–3.2) 1.6 (0.6–2.6)
   Avuncular pairs 84    1.1 (0.5–1.7) 1.3 (0.3–2.3)
   Common τ1, τ2   51.3 (48.4–54.3) 79.2 (61.9–96.5)   
Constrained model 1421 49.1 (45.6–52.7) 62.2 (54.7–69.6) 1.5 (1.3–1.7) 1.4 (1.3–1.6)