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Table 2 Maximum L-scores and positions on each chromosome for expression phenotypes selected for LOD score >3, selected at random, and simulated null data

From: The feasibility of oligogenic combined segregation and linkage analysis in CEPH pedigrees

  Trait
  202546_at (h2 = 0.399; p = 0.1468)a   204418_x_at (h2 = 0.420; p = 0.1439)   33307_at (h2 = 0.383; p = 0.0002)   218264_at (h2 = 0.161; p = 0.0063)   Simulated
Chr Position (cM)b L-score Position (cM) L-score Position (cM) L-score Position (cM) L-score L-score
1 -- 0.5 142.6c, d 477.7 -- 3.6 -- 1.2 0.8
2 115.5c, d 125.9 -- 3.8 -- 2.1 -- 3.9 0.5
3 -- 0.5 --e 1.0 25.5 19.1 39.5 17.6 0.5
4 -- 0.5 -- 1.9 -- 3.2 -- 2.2 0.5
5 -- 0.5 -- 1.1 -- 2.5 -- 4.7 0.8
6 -- 0.5 -- 0.8 -- 1.4 -- 6.6 0.4
7 -- 1.7 --f 0.5 -- 4.5 -- 1.3 1.2
8 -- 0.4 -- 1.4 -- 3.2 -- 3.5 1.2
9 -- 0.4 --e 0.5 --f 2.1 -- 9.4 1.0
10 -- 0.6 -- 0.8 -- 1.4 --c 1.1 0.9
11 -- 0.4 -- 0.9 -- 1.4 46.5e 16.5 1.5
12 -- 0.8 -- 0.3 -- 4.3 -- 2.1 0.6
13 -- 0.5 -- 0.6 -- 5.9 -- 2.7 0.5
14 -- 0.4 --e 1.8 -- 1.6 -- 2.1 0.6
15 -- 0.4 -- 0.7 -- 2.0 -- 1.9 0.4
16 -- 0.5 -- 0.4 -- 0.7 -- 1.1 1.1
17 -- 0.5 -- 0.6 -- 0.7 -- 2.7 0.7
18 -- 0.4 -- 0.3 -- 1.2 -- 1.6 0.5
19 -- 0.4 -- 1.3 -- 0.5 5.1 9.7 0.5
20 -- 0.4 -- 0.4 -- 0.7 -- 0.9 0.4
21 -- 0.5 -- 0.8 -- 2.2 -- 6.0 0.7
22 -- 0.5 -- 0.6 61.5c, d 163.2 -- 1.9 0.5
  1. aSharpiro-Wilk normal test p-value
  2. b--, L-scores <7.3
  3. cChromosome with structural gene
  4. dLOD > 3
  5. e2 > LOD > 1.5
  6. f3 > LOD > 2