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Table 1 Top-ranking associations

From: Bayesian hierarchical modeling of means and covariances of gene expression data within families

    

Top SNPs used in the prediction

Phenotypea

Probe

R 2

P(R2 > 0)

SNP1

πnm

SNP2

πnm

SNP3

πnm

SNP4

πnm

HSD17B12

217869_at

0.25

0.988

rs1453389b

1.00

rs916482

1.00

rs1425151

0.40

rs509628

0.28

C11orf10

218213_s_at

0.12

0.986

rs916482

1.00

      

AMPD3

207992_s_at

0.19

0.985

rs2029463b

0.81

rs948215

0.80

rs1157659

0.21

rs1491846

0.17

FEZ1

203562_at

0.12

0.984

rs2029463

1.00

rs2155076

0.20

rs948215b

0.11

  

ADM

202912_at

0.11

0.982

rs916482

1.00

      

STIP1

213330_s_at

0.11

0.981

rs916482

0.99

rs1319730

0.33

    

DDB1

208619_at

0.15

0.978

rs1530966

0.91

rs597345

0.54

rs1499511

0.10

  

FADS1

208964_s_at

0.14

0.974

rs1216592

0.85

rs1605026

0.38

rs591804

0.35

  

TPP1

200743_s_at

0.13

0.970

rs916482

0.94

rs1157659

0.14

rs902215b

0.14

  

RBM14

204178_s_at

0.10

0.966

rs916482

0.98

rs674237

0.10

    

HMBS

203040_s_at

0.13

0.963

rs86392

0.49

rs916482

0.47

rs1319730b

0.44

rs1945906

0.20

PPME1

49077_at

0.11

0.958

rs916482

0.82

rs2155001

0.16

    

CD44

204490_s_at

0.12

0.957

rs702738

0.34

rs916482

0.28

rs1319730

0.28

rs1453390b

0.17

NRGN

204081_at

0.10

0.946

rs2029463

0.93

rs961746

0.16

rs509628

0.15

  

NDUFS8

203190_at

0.11

0.944

rs86392

0.68

rs1319730

0.33

rs1945906

0.32

  

PSMD13

201232_s_at

0.09

0.923

rs916482

0.91

rs1319730

0.12

    
  1. aPhenotypes ranked by most significant coefficient of determination, and some of their top associated SNPs ranked by average πnm.
  2. bcis-acting interaction, defined as the SNP being within 10 MB of the phenotype probe alignment.