Skip to main content

Advertisement

Table 1 NARAC data, additive model p-values and effects for the anti-CCP Blom-transformed and the IRT latent variable dataa

From: Rheumatoid arthritis, item response theory, Blom transformation, and mixed models

  Anti-CCP Blom-transformed IRT latent variable
No. SNP p-value Additive effect STD bp SNP p-value Additive effect STD bp
1 rs189512 0.00067 -0.14680 0.04294 6923632 rs2876143 0.00816 0.07944 0.02993 8928623
2 rs214527 0.01890 -0.11800 0.05014 18399329 rs1863995 0.04430 -0.05370 0.02665 13565596
3 rs1402405 0.02528 0.08417 0.03755 24198476 rs736794 0.04758 -0.04813 0.02425 41044688
4 rs1224485 0.02145 0.08928 0.03874 37043628 rs1009130 0.00301 0.08090 0.02716 58068726
5 rs1738240 0.01339 0.10040 0.04051 38810588 rs977382 0.02981 0.06241 0.02866 62057200
6 rs533393 0.00897 -0.10350 0.03951 81645240 rs1040802 0.01273 -0.06005 0.02403 63469278
7 rs1180237 0.01758 0.09720 0.04085 83939524 rs2076874 0.00397 0.06580 0.02276 64150527
8 rs910563 b 0.01025 0.10250 0.03983 88054481 rs1630182 0.02261 -0.05252 0.02298 64205048
9 rs1051131 0.04853 0.07951 0.04024 88217142 rs1370436 0.03343 0.05014 0.02352 74520012
10 rs2144363 0.02680 0.19480 0.08778 92037502 rs910563 0.03853 0.04794 0.02312 88054481
11 rs6454855 0.04535 0.07830 0.03906 92071536 rs2610715 0.01464 -0.05937 0.02425 89260502
12 rs716192 0.04829 -0.08171 0.04131 96557287 rs240153 0.04093 -0.04727 0.02307 101112733
13 rs1321807 0.02545 0.08678 0.03876 117730562 rs239229 0.02728 -0.05129 0.02318 101151573
14 rs941815 0.04541 -0.08273 0.04128 123901148 rs239189 0.03231 0.04970 0.02317 101174385
15 rs839556 0.04100 0.08086 0.03950 142852448 rs1158747 0.03314 -0.05161 0.02417 112546220
16 rs923459 0.00991 0.10150 0.03927 159471138 rs763075 0.00505 0.06554 0.02330 122192096
17 rs294882 0.02322 -0.09232 0.04059 159512287 rs1033540 0.04603 -0.04924 0.02463 131717872
18       rs225604 0.00643 0.06488 0.02373 142433136
19       rs1931992 0.00209 0.07516 0.02433 142581777
20       rs2151913 0.03291 -0.05082 0.02377 150161633
21       rs718527 0.01903 -0.05770 0.02454 152501127
22       rs231958 0.01449 0.06105 0.02490 155786394
23       rs923459 0.01838 0.05568 0.02356 159471138
24       rs409359 0.04983 -0.04526 0.02303 159854284
25       rs916331 0.01358 0.05892 0.02380 167379847
  1. aSee the Discussion paragraph for details on the genes that have significant SNPs part of this study. bBold text indicates significant SNPs replicated in the association tests for two different RA outcomes.