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Table 1 PTPN22 SNP data: study descriptives

From: Meta-genetic association of rheumatoid arthritis and PTPN22using PedGenie 2.1

 

NARAC Study 1a

NARAC Study 2a

 

Cases

Controls

Cases

Controls

 

N

%

N

%

N

%

N

%

RA

446

 

767

 

839

 

854

 

   Family-based

446

100.0

103

13.4

839

100.0

--

--

   Independent

--

--

664

86.6

--

--

854

100.0

   Age at onsetb

39

13.9

--

--

39

13.1

--

--

   RF+ (≥ 11)

346

77.5

--

--

708

84.4

--

--

   RF- (< 11)

89

20.0

--

--

129

15.4

--

--

   RF unknown

11

2.5

--

--

2

0.2

--

--

   anti-CCP+ (≥ 49)

267

59.9

--

--

545

65.0

--

--

   anti-CCP- (< 49)

141

31.6

--

--

274

32.7

--

--

   anti-CCP unknown

38

8.5

--

--

20

2.4

--

--

  1. aStudy 1: 202 pedigrees with genotypes; Study 2: 463 pedigrees with genotypes.
  2. bMedian