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Table 1 PTPN22 SNP data: study descriptives

From: Meta-genetic association of rheumatoid arthritis and PTPN22using PedGenie 2.1

  NARAC Study 1a NARAC Study 2a
  Cases Controls Cases Controls
  N % N % N % N %
RA 446   767   839   854  
   Family-based 446 100.0 103 13.4 839 100.0 -- --
   Independent -- -- 664 86.6 -- -- 854 100.0
   Age at onsetb 39 13.9 -- -- 39 13.1 -- --
   RF+ (≥ 11) 346 77.5 -- -- 708 84.4 -- --
   RF- (< 11) 89 20.0 -- -- 129 15.4 -- --
   RF unknown 11 2.5 -- -- 2 0.2 -- --
   anti-CCP+ (≥ 49) 267 59.9 -- -- 545 65.0 -- --
   anti-CCP- (< 49) 141 31.6 -- -- 274 32.7 -- --
   anti-CCP unknown 38 8.5 -- -- 20 2.4 -- --
  1. aStudy 1: 202 pedigrees with genotypes; Study 2: 463 pedigrees with genotypes.
  2. bMedian