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Table 1 Heritability (h2), association testing (minimum p-values of SNP and haplotype association test), and linkage analysis (maximum LOD scores)a

From: Analysis of variation in NF-κB genes and expression levels of NF-κB-regulated molecules

     NFKB1 (106 SNPs) NFKB2 (3 SNPs) REL (16 SNPs) RELA (3 SNPs)
Phenotype Probe h 2 h2 p-Value SNP Haplotype LOD SNP Haplotype LOD SNP Haplotype LOD SNP Haplotype LOD
BCL2A1 205681_at 0.42 0.0008 0.029 0.040 <1.00 0.04 >0.05 <1.00 >0.05 >0.05 1.70 >0.05 >0.05 1.61
BIRC2 202076_at 0.48 0.0003 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 1.24
CD40 35150_at 0.49 0.0003 >0.05 >0.05 <1.00 0.01 >0.05 <1.00 0.28 0.047 2.17 >0.05 >0.05 1.31
CD44 204490_s_at 0.46 0.0004 0.034 0.009 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00
CD80 207176_s_at 0.49 0.0003 0.025 0.017 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00
CFLAR 211317_s_at 0.48 0.0003 >0.05 >0.05 <1.00 0.05 >0.05 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00
CR2 205544_s_at 0.47 0.0003 >0.05 >0.05 <1.00 0.02 >0.05 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00
FAS 204780_s_at 0.43 0.0007 0.032 >0.05 1.38 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00
ICAM1 202638_s_at 0.46 0.0004 0.025 0.05 <1.00 0.05 >0.05 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00
IL15 205992_s_at 0.41 0.0009 0.013 >0.05 <1.00 >0.05 >0.05 <1.00 0.038 0.05 <1.00 >0.05 >0.05 <1.00
IRF1 202531_at 0.42 0.0009 0.031 0.022 2.54 >0.05 >0.05 1.45 0.01 0.05 <1.00 >0.05 >0.05 <1.00
JUNB 201473_at 0.41 0.0009 0.033 >0.05 <1.00 0.01 >0.05 <1.00 0.0082 0.016 <1.00 >0.05 >0.05 <1.00
MYC 202431_s_at 0.51 0.0002 >0.05 >0.05 <1.00 >0.05 >0.05 <1.00 >0.05 >0.05 1.37 >0.05 >0.05 <1.00
SLC2A5 204429_s_at 0.47 0.0003 >0.05 >0.05 <1.00 0.03 >0.05 1.01 0.02 0.002 <1.00 >0.05 >0.05 <1.00
VCAM1 203886_s_at 0.43 0.0007 0.011 0.010 <1.00 >0.05 >0.05 <1.00 0.01 0.048 <1.00 >0.05 >0.05 <1.00
  1. aNo suggestive results were found for RELB genotypes (8 SNPs) and any phenotype. HapMap data was used for association testing; GAW15 data was used for linkage analysis.
  2. bBold indicates p-values of SNP or haplotype association test ≤0.05 or LOD score of linkage analysis >1.