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Table 1 Type I error and power

From: Association testing by haplotype-sharing methods applicable to whole-genome analysis

 

Type I errora

Powerb

Method

0.05

0.005

0.0005

Chr 6

Chr 11

Chr 18

Single-SNP association

0.051

0.0048

0.00057

1.0

0.7

0.1

Haplotype association

0.053

0.0052

0.00051

1.0

0.8

0.1

HSS

0.052

0.0046

0.00031

1.0

1.0

0.1

CROSS

0.051

0.0051

0.00061

1.0

1.0

0.4

  1. aType I results at three different significance levels were determined from the Replicates 1 to 10 of SNPs on all chromosomes except 6, 11, and 18.
  2. bPower is determined as the fraction of replicates showing a significant result (p < 0.05/9187) in a 1-Mb region around SNP6_153 on chromosome 6, SNP11_389 on chromosome 11, and SNP18_269 on chromosome 18.