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Table 1 Properties of 95% confidence intervals obtained from TreeLD and WAL

From: Fine-scale linkage disequilibrium mapping: a comparison of coalescent-based and haplotype-clustering-based methods

 

TreeLD mutation ratesb,c

 

Choice of SNPsa

0.2

0.4

0.6

0.8

1.0

WALb,d

Tagging SNPs

35% (2.9)

37% (2.8)

45% (3.3)

55% (3.7)

60% (3.8)

96% (5.7)

ES SNPs

65% (2.0)

59% (2.2)

59% (2.3)

59% (2.3)

65% (2.3)

96% (3.8)

  1. aEither 50 equally spaced (ES) SNPs (causal locus included) or 52 tagging SNPs (causal locus missing) are used.
  2. bEmpirical coverage of the disease locus (entries outside the parentheses) and the average length of the intervals (entries inside the parentheses, in 105 bp) are given.
  3. cTreeLD was applied to 20 replicates.
  4. dWAL was applied to 100 replicates.
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BMC Proceedings

ISSN: 1753-6561

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