Figure 1

Schematic representation of the local scores method. A, scores X _i (e.g., Pearson chi-squared statistics for case-control genotype frequencies) at marker locations along a chromosome. B, Scores ${X^{\prime }}_i$ at marker locations along a chromosome; ${X^{\prime }}_i$ = X _i - δ, δ being the value of statistic X _i at the 5% level.