Skip to main content

Table 1 Mean (SD) number of positive SNPs at significance level α and fraction of samples f in stage one and for sample sizes 100, 200, and 300 for each method (one-stage design, two-stage design, and two-stage design with clustering)

From: Marker selection for whole-genome association studies with two-stage designs using dense single-nucleotide polymorphisms

   100 200 300
α f 1 stage 2 stage 2 stage-c 1 stage 2 stage 2 stage-c 1 stage 2 stage 2 stage-c
0.05 0.3   15.8(± 0.42) 6.8(± 0.20)   27.6(± 0.54) 10.7(± 0.25)   39.7(± 0.62) 15.0(± 0.29)
  0.4 17.9(± 0.44) 16.1(± 0.43) 6.5(± 0.19) 31.1(± 0.62) 28.3(± 0.58) 11.3(± 0.25) 44.9(± 0.71) 40.1(± 0.63) 15.3(± 0.27)
  0.5   16.1(± 0.42) 6.9(± 0.18)   28.2(± 0.56) 11.4(± 0.26)   40.5(± 0.64) 15.7(± 0.27)
0.01 0.3   14.0(± 0.41) 6.0(± 0.20)   24.6(± 0.48) 9.8(± 0.23)   35.6(± 0.57) 13.5(± 0.27)
  0.4 15.7(± 0.41) 14.2(± 0.38) 6.0(± 0.18) 27.6(± 0.54) 25.0(± 0.47) 10.4(± 0.22) 39.4(± 0.62) 36.0(± 0.54) 14.0(± 0.26)
  0.5   14.2(± 0.39) 6.2(± 0.16)   25.1(± 0.48) 10.3(± 0.23)   36.1(± 0.56) 14.3(± 0.25)