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Table 2 Power comparison of various statistics at SNP387 on chromosome 11

From: Two-stage analysis strategy for identifying the IgM quantitative trait locus

   α = 0.005 α = 0.001
π 1 Statistics Reverse normal Fisher Reverse normal Fisher
1 T 2 0.35 0.35 0.09 0.09
  Wilcoxon 0.89 0.89 0.74 0.74
0.3 T2, T2 a 0.31 0.23 0.05 0.03
  Wilcoxon, Wilcoxon 0.86 0.81 0.61 0.60
  Adaptive 1b 0.86 0.81 0.61 0.60
  Adaptive 2c 0.76 0.69 0.51 0.43
0.5 T2, T2 a 0.26 0.22 0.07 0.04
  Wilcoxon, Wilcoxon 0.81 0.81 0.59 0.60
  Adaptive 1b 0.81 0.81 0.59 0.60
  Adaptive 2c 0.61 0.57 0.36 0.42
  1. aThe two statistics are those used at the first and second stages, respectively.
  2. bThe prespecified statistic used for the exploratory stage is Wilcoxon.
  3. cThe prespecified statistic used for the exploratory stage is T2.