Skip to main content

Table 3 Penetrance and coupling associated with PTPN22 stratified by rheumatoid factor (RF) status

From: Modeling of PTPN22 and HLA-DRB1 susceptibility to rheumatoid arthritis

 

Patient status

 

Genotype

RF+

RF-

Total sample

Penetrancea

   

   TT

1

1

1

   TC

0.55

0.34

0.52

   CC

0.19

0.20

0.19

Coupling

   

   T

0.96

0.99

0.97

   C

0.07

0.13

0.07

-2*log likelihood

1677.152

367.36

2047.328

p-value

0.33

0.23

0.20

  1. aThe global penetrance is set to 0.37 in all models. The reference genotype is TT.
Back to article page

BMC Proceedings

ISSN: 1753-6561

Contact us