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Table 2 Power for detecting SNP 3455 based on the dense SNP data of chromosome 6 by using 150 families and 200 unrelated controls

From: Genome-wide association tests by two-stage approaches with unified analysis of families and unrelated individuals

 

Two children in each familyb

One child in each familyb

α a

PDT

T pc

T cc

T cb

PDT

T pc

T cc

T cb

0.01

 

0.93

0.15

0.96

 

0.66

0.13

0.87

0.05

 

0.95

0.39

0.96

 

0.65

0.29

0.8

0.1

0.83

0.96

0.54

0.96

0.53

0.64

0.4

0.75

0.3

 

0.91

0.77

0.91

 

0.58

0.53

0.61

0.5

 

0.88

0.81

0.88

 

0.56

0.54

0.56

  1. aα, the cut-off p-value of the test in the first stage
  2. bPDT, pedigree disequilibrium test; T pc , test comparing all parents to controls; T cc , test comparing affected and unaffected parents; T cb , combined T pc and T cc
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BMC Proceedings

ISSN: 1753-6561

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