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Table 2 Properties of 95% confidence sets constructed with CSI-MLS and CSI-Mean

From: Two-step intermediate fine mapping with likelihood ratio test statistics: applications to Problems 2 and 3 data of GAW15

No. ASPs Strategy With parental genotypesa Without parental genotypesa
   CSI-MLS CSI-Mean RR (%) CSI-MLS CSI-Mean RR (%)
250 MS1 28.1 (1.00) 36.1 (1.00) 22 29.6 (1.00) 38.7 (1.00) 24
  MSINT 22.8 (1.00) 30.4 (1.00) 25 23.2 (0.98) 33.4 (1.00) 31
  SNP1 24.6 (1.00) 31.6 (1.00) 22 26.8 (1.00) 37.3 (1.00) 28
  TRUE 21.5 (0.91) 27.2 (0.95) 21 29.8 (0.96) 35.5 (0.94) 16
500 MS1 21.8 (1.00) 28.8 (1.00) 24 21.8 (1.00) 31.6 (1.00) 31
  MSINT 15.4 (1.00) 21.5 (1.00) 28 13.5 (0.97) 23.4 (1.00) 42
  SNP1 17.0 (1.00) 23.1 (1.00) 26 18.6 (0.99) 29.9 (1.00) 34
  TRUE 15.2 (0.92) 20.1 (0.97) 24 24.5 (0.95) 31.8 (0.98) 23
750 MS1 18.4 (1.00) 24.1 (1.00) 24 17.6 (1.00) 27.1 (1.00) 35
  MSINT 12.2 (1.00) 16.7 (1.00) 27 9.1 (0.95) 17.8 (1.00) 49
  SNP1 14.2 (1.00) 18.6 (1.00) 24 14.4 (0.98) 24.9 (1.00) 42
  TRUE 11.9 (0.94) 16.3 (0.96) 27 21.3 (0.97) 28.5 (0.94) 25
  1. aEmpirical proportions of confidence sets that contain the disease gene locus are given in parentheses. The relative reduction in length obtained by using CSI-MLS in place of CSI-Mean is given by RR = Mean length of CSI-Mean  Mean length of CSI-MLS Mean length of CSI-Mean  × 100 % MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=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@9DA8@