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Table 3 Common haplotype analysis of the S2 candidate region

From: Association mapping of susceptibility loci for rheumatoid arthritis

Code S2Haplotypea Frequency χ2 p
  - - - - + + + + - + + + - - - + + + + - + Total Case Control   
H 1 1 2 1 2 2 1 1 1 1 2 2 1 2 2 1 2 2 1 2 2 2 0.339 0.343 0.336 0.10 0.8
H 2 2 1 2 1 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 1 2 0.256 0.274 0.238 3.13 0.08
H 3 2 1 2 1 2 1 1 1 1 2 2 1 2 2 1 2 2 1 2 1 1 0.100 0.089 0.110 2.26 0.1
H 4 2 1 2 1 1 2 2 2 1 1 1 2 2 2 1 2 1 1 2 2 1 0.079 0.074 0.084 0.63 0.4
H 5 1 2 1 2 1 2 2 2 1 1 1 2 2 2 1 2 1 1 2 2 1 0.075 0.056 0.094 9.57 0.002
  1. aSNPs from left to right: rs813043, rs784254, rs711745, rs784251, rs4800995, rs784237, rs796743, rs784235, rs784233, rs4800996, rs3745044, rs784232, rs1642295, rs784240, rs1362781, rs2306163, rs931040, rs4996482, rs899101, rs899102, rs1031830, '+', '-' denote a SNP with nominal association (+) or no association (-) with RA. '1', '2' denote the alleles of a SNP.