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Table 3 Common haplotype analysis of the S2 candidate region

From: Association mapping of susceptibility loci for rheumatoid arthritis

Code

S2Haplotypea

Frequency

χ2

p

 

- - - - + + + + - + + + - - - + + + + - +

Total

Case

Control

  

H 1

1 2 1 2 2 1 1 1 1 2 2 1 2 2 1 2 2 1 2 2 2

0.339

0.343

0.336

0.10

0.8

H 2

2 1 2 1 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 1 2

0.256

0.274

0.238

3.13

0.08

H 3

2 1 2 1 2 1 1 1 1 2 2 1 2 2 1 2 2 1 2 1 1

0.100

0.089

0.110

2.26

0.1

H 4

2 1 2 1 1 2 2 2 1 1 1 2 2 2 1 2 1 1 2 2 1

0.079

0.074

0.084

0.63

0.4

H 5

1 2 1 2 1 2 2 2 1 1 1 2 2 2 1 2 1 1 2 2 1

0.075

0.056

0.094

9.57

0.002

  1. aSNPs from left to right: rs813043, rs784254, rs711745, rs784251, rs4800995, rs784237, rs796743, rs784235, rs784233, rs4800996, rs3745044, rs784232, rs1642295, rs784240, rs1362781, rs2306163, rs931040, rs4996482, rs899101, rs899102, rs1031830, '+', '-' denote a SNP with nominal association (+) or no association (-) with RA. '1', '2' denote the alleles of a SNP.