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Table 5 SNP density and accuracy – selection by tagging or equidistance

From: Association mapping of susceptibility loci for rheumatoid arthritis

r2/LDU/kb (kb/SNP)

No. of SNPsa

Location errorb

ΛA - ΛD

  

Tagger

E_LD

E_kb

Tagger

E_LD

E_kb

Full (4)

189/189/189

0

0

0

79

79

79

1.0/0.002/1 (5)

160/163/150

1

0

-2

62

69

68

0.8/0.036/5 (11)

78/74/64

-14

4

-5

21

18

20

0.6/0.071/9 (15)

59/55/48

-26

-37

-3

10

11

10

0.4/0.134/14 (21)

43/39/33

-27

25

-5

12

11

8

0.2/0.300/26 (33)

28/21/20

-35

33

-180

7

9

1

  1. aFor the studied region for Tagger, Equal LD (E_LD) and kb (E_kb) distance, respectively.
  2. bAssuming S1 is the "disease locus," the region was fixed at 10 LDUs centering at S1 and the location error was calculated as S-53,306 kb.