Table 3 Selected expression phenotypesa with significant evidence for linkage (LOD score ≥ 3.4) from genome scans identified in all data sets normalized by three different methods
From: Impact of normalization and filtering on linkage analysis of gene expression data
| Â | Â | LOD score | Â | ||
|---|---|---|---|---|---|
Gene symbol | Chromosomal location | RMA | GCRMA | PLIER | cis/trans |
MCP | 1q32 | 4.19 | 4.12 | 5.29 | trans |
YT521 | 4q13.2 | 3.79 | 4.51 | 4.38 | trans |
RNF11 | 1pter-p22.1 | 4.21 | 3.45 | 4.57 | trans |
RASSF3 | 12q14.2 | 4.99 | 4.60 | 5.17 | trans |
RAB6C | 2q31 | 6.32 | 6.12 | 4.46 | trans |
FAM8A1 | 6p22-p23 | 4.62 | 4.75 | 5.20 | trans |
ZNF217 | 20q13.2 | 4.36 | 4.75 | 4.76 | trans |
CREB3 | 9pter-p22.1 | 3.60 | 4.41 | 3.48 | trans |
PRPSAP1 | 17q24-q25 | 4.97 | 3.54 | 4.28 | trans |
SPAG9 | 17q21.33 | 5.09 | 3.90 | 4.19 | trans |
SRPK2 | 7q22-q31.1 | 3.52 | 5.13 | 3.89 | trans |
LOC81558 | 17q21.33 | 3.96 | 5.44 | 4.36 | trans |
IRF2 | 4q34.1-q35.1 | 4.28 | 3.48 | 3.61 | trans |
BCL2 | 18q21.33|18q21.3 | 4.41 | 5.86 | 4.78 | trans |
PTPN22 | 1p13.3-p13.1 | 3.76 | 4.25 | 4.61 | trans |
SDCBP | 8q12 | 5.76 | 4.76 | 5.08 | trans |
OSBP | 11q12-q13 | 4.21 | 4.46 | 3.71 | trans |
PTPN1 | 20q13.1-q13.2 | 5.22 | 5.12 | 3.77 | trans |
RGS12 | 4p16.3 | 5.90 | 4.68 | 4.17 | trans |